[quote]bushidobadboy wrote:
Whilst I’m here and rambling, lol…
Are you aware of the link between histamine and it’s role as a neurotransmitter, in the regulation of sleep and wakefullnes? It is the most potent of the neuroTxs in this regard.
Now, NO-xplode causes vasodilation by triggering the release of nitrous oxide in the blood. Endothelial cells release NO and this causes them to relax, expanding the diameter of blood vessels.
However, it occurs to me that there is a link between NO and histamine, partly through the inflammatory process I believe.
You see, one of the stages of inflammation requires that blood supply to a damaged area is increased (hence the redness you see). Histamine is also released as part of this process, from mast cells. Histamine causes symptoms such as a runny nose during hayfever, etc - part of a standard immune response.
I am reaching here, but indulge me, lol.
So the NO-xplode triggers a release of NO, which causes incread bloodflow and which may be ‘seen’ by the body as part of an immune response. Another, linked part of that response is to release large amounts of histamine into the blood. Some of this crosses the blood brain barrier and acts as a neurotransmitter.
I am wondering if the reason you enjoy the NO-xplode so much is that the NO releasing properties cause a transient increase in blood histamine levels, which top up your diminished levels in the brain, and act as neurotransmitters there, helping to regulate/stimulate wakefulness.
Just a theory. Perhaps it is all the caffine instead, hahahaha!
Bushy[/quote]
sorry about confusing GABA with GHB. i wasn’t paying close enough attention. you really sound like you know what you are talking about.
not sure about the NO-xplode. it does have alot of caffeine. if i take it on an empty stomach 1 hour before workout i get the really pumped feeling that it is supposed to give. i do find myself taking it even on non-workout days if i have alot of work to do or whatever. it is good stuff.
i really have not tried the dedicated NO products like Nitrix…maybe i should try one to see if taken daily it helps with wakefullness ? ?