I'm currently on my first week of "hopefull" restart therapy. Going with KSman's protocol of 250iu eod for 4-6 weeks, then changing over to a serm. Originally, I was going to utilize nolvadex, but after doing some research, it seems that nolvadex & Zoloft both use the enzyme CYP2D6, and for this reason nolvadex becomes less effective.
My first question is has anyone else ever used nolvadex with success while taking Zoloft? Also, would clomid be a better option as is does not interact negatively with Zoloft?