I tip my hat to you then, haha. the coldest I've ever gone out in is like -20F, my water bottle froze and when I took my bala clava (face-mask) off for ten seconds it felt like the inside of my nose and corner of my eyes started to freeze. You truly start to wonder that if you stop running out there, if you'll just freeze to death.
there feels to be a big difference from -18 to -20, so I can only imagine -22. (I only braved -20 a couple of times as well.) I try to go outside every-day to slowly adjust my tolerance to the cold I find skipping even one day where the temperature is consistently dropping to be a huge mistake.