I started TRT in early August 2016 after lurking here for a while and absorbing the stickies. I did the temp test for Thyroid before starting (and was low) and did a course of Iodoral which brought it up to spec during the first couple of weeks of my TRT.
60 years old
5'10 185lbs, 25% bf
current blood work:
CBC With Differential/Platelet
WBC 4.9 3.4-10.8 x10E3/uL
RBC 4.89 4.14-5.80 x10E6/uL
Hemoglobin 15.3 12.6-17.7 g/dL
Hematocrit 46.6 37.5-51.0 %
MCV 95 79-97 fL
MCH 31.3 26.6-33.0 pg
MCHC 32.8 31.5-35.7 g/dL
RDW 14.0 12.3-15.4 %
Platelets 189 150-379 x10E3/uL
Neutrophils (Absolute) 2.3 1.4-7.0 x10E3/uL
Lymphs (Absolute) 2.0 0.7-3.1 x10E3/uL
Monocytes(Absolute) 0.5 0.1-0.9 x10E3/uL
Eos (Absolute) 0.1 0.0-0.4 x10E3/uL
Baso (Absolute) 0.0 0.0-0.2 x10E3/uL
Immature Granulocytes 0
Immature Grans (Abs) 0.0 0.0-0.1 x10E3/uL
Comp. Metabolic Panel (14)
Glucose, Serum 113 HIGH 65-99 mg/dL
BUN 21 8-27 mg/dL
Creatinine, Serum 1.09 0.76-1.27 mg/dL
eGFR If NonAfricn Am 73 >59 mL/min/1.73
eGFR If Africn Am 85 >59 mL/min/1.73
BUN/Creatinine Ratio 19 10-22
Sodium, Serum 137 136-144 mmol/L
Potassium, Serum 4.2 3.5-5.2 mmol/L
Chloride, Serum 99 97-106 mmol/L
Carbon Dioxide, Total 23 18-29 mmol/L
Calcium, Serum 9.2 8.6-10.2 mg/dL
Protein, Total, Serum 6.7 6.0-8.5 g/dL
Albumin, Serum 4.5 3.6-4.8 g/dL
Globulin, Total 2.2 1.5-4.5 g/dL
A/G Ratio 2.0 1.1-2.5
Bilirubin, Total 1.3 HIGH 0.0-1.2 mg/dL
Alkaline Phosphatase, S 63
AST (SGOT) 22
ALT (SGPT) 19
Testosterone, Total, LC/MS 1117 348 - 1197 ng/dL
Free Testosterone (Direct) 19.2 7.2 - 24.0 pg/mL
Estradiol (Roche ECLIA) 7.0 7.6-42.6
The first two months went pretty much as expected. I started out at 200mg Test-Cyp per week split into two shots. I also take 500iu HCG with each shot and 0.5mg of Anastrozole.
I don't think the doc is keeping close enough eye on things so I've been doing my own private labs every 30 days.
First set of private labs after a month showed me >1500 so I backed off to 140mg per week where I am now. Still the same HCG and Anastrozole. On my first private lab at one month my estradiol was about 25 and a month later was 27. This last set it crashed to 7. I have some of the classic low E2 symptoms (feel flat, slight depression, cranky, brain fog, etc) but I know how to fix that by titrating the Anastrozole.
The problem that concerns me is that my blood sugar (which I've never had any problem with) is now crazy. In the next lab (above) it is 113, so I started checking my fasting blood sugar in the mornings. It is consistently over 120. This morning it was 135! Can the low E2 cause this?
My diet is fairly slow carb, nothing that should cause crazy fluctuations. I used to be nearly keto, but eased up after starting the TRT. The first two months I gained about 6lbs of muscle (according to BIA, which I know, is only a rough guess) and lost about 10lbs of fat. I've been in a slight calorie deficit lately to lose some more fat and it looks like a little of the muscle may have come off with its but losing weight is much easier than before the TRT.
I work out lifting three times a week until recently (minor injury that I'm trying to recover) and I swim on days that I don't lift.
Thanks to this forum (and KSMan's excellent advice) I think I've avoided a lot of time wasting and I caught this early...