I see some suggestions about doing deadlifts, gpp, intervals etc, but really if he's looking for the endurance to run around for 1 hr straight with some sprints, his best bet is to run around for 1 + hr occasionally and some of the runs throw in some pick-ups to train for the ability to switch gears. If his goal were something along the lines of starting and stoping with breaks, i'd suggest the GPP, deads, etc.
Physiologically, there is a difference between doing 10 x 20 for squats with 10 sec rest and 1 hr out on the roads. The reason why the hour out on the roads can be catabolic, is, as many posters stated, adaptive for the body to run those distances for homeostasis. Also, the body switches type II fibers to type I, which would give a "catabolic" effect in the sense that you're losing these dense muscle fibers for the slow-twitch less dense muscle fibers. The type II fibers get exhausted and after this happens, you're only using type I, if your body does not have enough, it is very good, over a period of time, to switch the type II to type I.
Hopefully somebody got through that to understand what I was trying to say and comment on it. Just my observations from an endurance athlete aspect.