I'm looking at a recipe from the Precision Nutrition book and I didn't see any specific suggestion as to the type of Splenda. I didn't realize there were different types. Maybe I'll take a closer look.
None of those things have been shown at all convincingly. As far as cancer goes, it's impossible to know. It hasn't been around long enough. The evidence that it acts like sugar and afffect insulin has been discredited. And I personally happen to know several diabetics who make use of splenda with zero effect on their insulin and zero impact on there craving sugar. And who said it causes you to hang on to fat?
I've read a little bit about Splenda (sucralose) a while ago. I think that while it can be linked to cancer (in lab mice), they have to consume an ungodly amount for it to do anything. In other words, I still use Splenda.
That seems to be the case for a lot of the cancer-linked testing done on rodents. At the dosages those rats/mice are given, damn near anything would cause cancer. You can't assault a body with an insane amount of anything without some type of negative reaction.
If I were to consume 40 gallons of milk, or 10 pounds of splenda, or whatever, a day, I bet I'd develop some type of cancer. I just don't find a lot of those tests all that relevant to the teaspoon of splenda being ingested by a 200lb. athlete....
The question that we should be asking is: Is there anything that DOESN'T give lab rats cancer? You could feed a lab rat spring water and super-sloppy blowjobs and the little fucker would have a 12 pound tumor in a week.