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What Went Wrong with My Clomid/Enclomiphene Experience?

Due to my T dropping to 300-400, my endo agreed to let me try clomid. Trying to figure out if it’s a flop, and make a decision on what to do next. Your input is greatly appreciated. I’ve highlighted some key points too.

Tldr: clomid worked great then started getting moody, tried enclomiphene of unknown quality, helped with mood but libido still weak. Time to give up on these?

My experience is almost identical to this guy’s: http://www.peaktestosterone.com/forum/index.php?topic=13993.45

Day 1 - 25mg - felt a huge difference. Not placebo as I was convinced it’d do nothing good, and in the past I’ve been convinced that I’d found the problem elsewhere (and nothing happened). Libido up, talking dirty to my girlfriend again, confident, more energy, even music sounding lifelike again. Amazing!

Day 2 - felt great still, did not dose

Day 3 - 25mg - made a big difference but not as big as day 1

Day 4 - felt pretty good

Day 5 - 12.5mg - after reading about high dose side effects, decided to lower my dose. Took it in the AM and got really really moody. Eased up later, felt pretty good still, but not nearly as great as the past few days.

Day 6 - started declining, getting depressed. After reading about thyroid stuff and iodine, took a ton of iodine via seaweed.

Day 7 - 12.5mg - started getting emotional. Body temp upon waking is under 97. Went for a blood test. T was at 599, E2 at 28 (barely elevated). No more libido or confidence boost really.

-STOPPED CLOMID, STARTED enclomiphene- (from internet website, no lab test available upon asking)

Day 8 - 25mg endo - emotional sides start reversing, feeling great again! Got some weird head rush. This is it! Hours later, feels like it wore off. Weird. Also took cialis this day, and PDE5 inhibitors always raise my libido as well.

Day 9 - 25mg endo - less of a rush, libido high, wore off again later. Noticing I feel really tired and spacey when it wears off. Also sleeping more. Body temp over 97 again.

Day 10-12 - alternating 12.5mg/25mg endo - benefits diminshing. **Music not sounding good anymore, starting to get depressed again. ** Got drunk one night.

Day 13 - 25mg endo - barely getting out of bed now (like before clomid) but felt slightly better after 25mg endo. Went to visit gf, barely getting it up. Low libido. Tried taking cialis, barely did anything (very abnormal). Getting some morning wood, but definitely not working 100% down there.

Day 14 - did not take anything, barely getting out of bed, even worse. Music sounds super uninspiring. Pretty depressed again. Able to get it up, but only briefly, girlfriend asking why I don’t want to fuck her. Confidence definitely back down to where it was pre-clomid (being needy waiting for girl to text me, snappy with friends, acting like a retired old man, not caring about my business).


My best guess is that I had an average clomid experience, where the benefits quickly wear off, even though my E2 was not that high. Wondering if it was the iodine rather than the clomid.

Also thinking the endo is either not endo, or is super weak. I’ve also heard endo failed tests as it caused libido issues (thought to be related to SBGH I’ve read). I’ve never been so disinterested in sex as I am now, it’s weird. Or could it be residual from the alcohol? I’m prone to 2-3 day hangovers.

What do you guys think? Is it worth trying clomid again or is this pretty standard? If it made me feel that good, should I consider TRT instead now? I’ve talked to Defy already, and I do qualify.

No results containing all your search terms were found.

Your search - ENDOCLOPHAMINE - did not match any documents.

Enclomifene acts by antagonizing the estrogen receptor (ER) in the pituitary gland, which reduces negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis, thereby increasing gonadotropin secretion and hence gonadal production of testosterone.[4] It is one of the two stereoisomers of clomifene, which itself is a mixture of 38% zuclomifene and 62% enclomifene.[

You were still taking clomid.
Your alternative choice should be Nolvadex.

from internet website - can be suspect.

Some guys simply feel crappy on clomid. Nolvadex does not do that.

Want to know what a SERM is doing? Also test LH and FSH to see how hypothalamus and pituitary are responding.

Higher doses can create too much LH causing high T–>E2 inside the testes and elevate E2 that could have dropped for when the labs were done.

Did you read everything in your other thread(s).
You should not again be spitting your threads.

Why are you not using Dostinex/cabergoline?

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My mistake, mispelled.

My endo refuses to let me try nolvadex. Either endo, for that matter. I’ve heard of libido issues on it as well though. But yea, I figure whatever I bought is either something else, underdosed, not 100% enclo, or who knows what.

I’ll ask her again to let me try it though. The next stop is TRT.

Edit: just called her again and left a message. Question - if I’m one of the unlucky ones who gets sexual sides from nolvadex, how long do they typically take to clear up? 5-7 day half life is brutal.

Got taken off of it as my prolactin is already quite low (5 on last test). It actually lowered my libido being on caber.