I’m not sure how old your family is, but Manitou springs just south of colorado springs is a fun little town to get away.
There is a cog railway that takes you up to the 14er pikes peak and serves you lunch. There is an awesome hike called the manitou “incline”, where an old cog railroad use to be. You have a beautiful view of colorado springs, but not something you want to try if the kids are too young.
Basically if you head west on highway 24 there is everything to do. Imitation cliff dwellings and an awesome gift shop, the north pole, dinosaur museum, many hikes, underground guided cave tours, seven falls - a waterfall that changes directions 7 times with great views (an elevator and stairs to the top), a couple more waterfalls, a nature center, you can drive up to the top of pikes peak yourself, and the cheyenne mountain zoo. All this stuff could fill multiple days and is all along highway 24.
You won’t be able to do all these things, but hey springs is great I live 45 minutes south and find myself up there a lot. I guess you could visit Biotest too. Do they give tours?
Have fun, colorado rocks!