What is TRT and What is NOT TRT

https://ascopubs.org/doi/10.1200/JCO.2010.28.5064

Related paper discussing subset of women who experience joint pain on standard AI dosing for cancer treatment.

Finally, it is intriguing to speculate that our findings in women receiving AIs who develop MS-AEs may provide insight into the “arthritis of the menopause” described by Cecil and Archer 85 years ago.29 AI therapy might be considered an estrogen-deprivation stress test that could provide novel insights into symptoms related to estrogen deprivation that occur during menopause—74% of women without breast cancer in the Women’s Health Initiative clinical trials reported joint pain.30

In summary, this GWAS identified four SNPs on chromosome 14 that were related to MS-AEs in patients receiving AI adjuvant therapy. The combination of four strong SNP signals and the equally strong functional linkage of these SNPs to AI effect focused our attention on these polymorphisms as possible biomarkers for risk for this important adverse drug reaction, on TCL1A as the potential link, and on cytokines as potential mechanistic factors. The determination of the mechanism of these MS-AEs would enable a focused approach to amelioration of symptoms, thus facilitating compliance and improving the benefits of AIs for women with early breast cancer.

what i got out of the article there is moderate decline but it can me attributed to poor diet and/or inactivity.

:exploding_head:

Damn dude those arm veins are like a wet dream to vampires.

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Beastly brother. It certainly takes time, effort and commitment to achieve that. Well done.

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:laughing:

4char

He’s right. Without a name nobody knows if the pics are real. And you are a gleaming example of what is not TRT "Almost three years ago I was 245 lb at probably 8-10% BF (Inbody) using 120-150 mg/week of Test / 120-160 mg / week Nandrolone Decanoate. My attempt at 325 mg/week of Test C ended badly " so a history of abuse of testosterone and utilization of anabolic steroids. And people want to listen to you because you have claimed yourself as a forum expert with no clinical experience whatsoever. How ridiculous when you won’t even identify yourself.By Identifying your true identity people would realize how little they should listen to you because you would be exposed. I find it quite amusing

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I take issue with this expectation. Why would anybody oust themselves? These are sensitive topics and while we all mean well, somebody could easily be targeted by identifying themselves. Also, I really find it highly unlikely these are photos of somebody else.

Aside from that you are welcome to take issue with prior substance use. I’m just not on the same page with saying its ‘not cool’ to hide your identity.

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I don’t recall this either. It would be pretty flagrant for any non medical professional to self proclaim expertise. That should be the bare minimum on top of a wealth of knowledge. Many frequent posters on here are considered ‘experts’ by those seeking knowledge but I can’t think of any that are active claiming ‘expertise’. Those in that past that did so… Danny (Dbossa), KSman, Physiologik and on and on have all been sent packing for one reason or another. Some were trying though and others were crooks.

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I think a few people saw 245 lbs and 10% BF without the context of height (6’5"). I am not trying to say it’s not impressive, but it isn’t in the category of I have to have pics to believe it.

For very developed individuals, one needs to weigh about 10 lbs more per inch of height to have similar physiques. Even for hobbyists that take this sorta seriously I’d say 7 lbs / in is fair.

IDK, if someone a more typical height (let’s say 5’9", since that is the U.S. average) claimed 245 lbs - ((77"-69")*7 lb/in)= 189 lbs at 10% body fat after light AAS use, I wouldn’t put that into the category of need pics to believe. I’ve seen this on natural lifters with good genetics (I’d classify this as somewhat rare genetics if they are actually 10% +/- 2%, maybe 1/20 - 1/50).

Now people do lie about stats that are not that impressive. I didn’t see it in this case though. The posts lined up with someone who had more than a surface level of knowledge AAS / PEDs. These things don’t ensure that the claims aren’t lies. Just IMO, it was more likely the claims were true or close to true (BF could be a bit off for example) than false. Occam’s razor type stuff.

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You as well, but way more obnoxious. One of the most dishonest, talking in circles, avoiding answering questions con artists on this forum.

See that’s where you’re all wrong and that’s why you want to identify yourself because you have no training and no experience whatsoever other than harming yourself with miss use and abuse including the use of anabolic steroids. Identify yourself so we can see your wonderful credentials that support you giving advice on forums that you do basically 24/7. Identify yourself and let’s see the credentials or are you like the other poster said “a coward”
And you should not speak on things you know nothing of. You have no idea where I have my men’s free testosterone levels. I’ll tell you a little secret. I have them where they have resolution in their symptoms and every parameter of health that we can measure improves. That’s where the free testosterone level is… it’s not a number that is aimed for it’s a number that is individual to that person. It’s where they feel, function, perform, and most importantly are their healthiest. Once again, every parameter of health that we can measure improves.
I’ve never personally done anabolic steroids. Never saw the upside. But I guess you’ve seen the downside from the harm you caused yourself. The pictures could be fake for sure. Who you are is someone you’re not willing divulge because it will then expose you as being the non-expert that you are. Just a forum doctor

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But here he is giving advice basically seven days a week 24 hours a day for the most part. Wouldn’t you want to know who you’re getting advice from? For all we know he’s a 22 year old girl in Kenya

You another one that spends all his/her time on forums that has no knowledge whatsoever. A total wanna be

Nobody likes you except maybe enackers.

This will be my actual last post because I have gotten rid of all social media in order to spend more time researching. The sad thing about forums like this is that people like you will take advice from complete strangers instead of actual experts. It’s really a sad space. Enackers he is a true success story. He had been mismanaged for years and had been following forum advice for years and was literally a shell of a human being. If you could literally see his before and now pictures it would put whoever read a lot is to shame. He had a truly amazing transformation both mentally and physically.

If only we were so lucky. You keep saying that just like Danny used to but then always return. Please just leave already, good riddance.

What education? It doesn’t matter how your anabolic steroids were obtained they’re still illegal and even if done through license medical professionals it’s still not off label use and it’s actually what’s going to close down all the clinics. The DEA is already investigating all of these clinics including some that you promote. Because of the online distribution of testosterone and anabolic steroids but all of these clinics we are all going to get shut down. They’re already looking into restricting off label use for testosterone just like they did growth hormone. So getting your anabolic steroids illegally from a clinic is no different from getting them off the streets. It’s silly when someone says that it’s above the board because they got it from a clinic that is using it illegally. Don’t believe me? I just talked to Rick Colins the most experienced attorney in the United States on the use of PEDs and defending people using PEDs etc. He is the first one to state that these clinics are inappropriately prescribing anabolic steroids and it cannot be defended whenever they are sued or the government intervenes. You have to have a true muscle wasting disease or a true FDA approved disorder in order to legally prescribe these steroids. Just because everyone’s doing it doesn’t mean that it’s legal and appropriate. So Mark my words in the very near future you will see the DEA and the government come after all of these clinics just like they did the pill meals with regard to pain management. Anyone that is prescribing anabolic steroids is not my peer. That license medical professional that you speak of will not have a license for long. Don’t take it from me take it from Rick Colins esq the leading attorney on anabolic steroids in the United States. I’ve had two colleagues that have notified me that they have been contacted by the DEA already who were investigating other clinics. Yes, this was related to the prescription of anabolic steroids. And what will happen in the end if they will shut down every clinic good or bad. They will make testosterone illegal to prescribe off label just like they did growth hormone and there’s a chance that along with that they’ll do just like with growth hormone as well making it illegal for doctor to prescribe testosterone unless a patient meets the strict criteria for hypogonadism. That will shut down everyone

Well here’s the rub. I don’t think anybody should take advice on here and run with it.
However a lot of forum members have anecdotal experiences and research knowledge that is a great springboard to speak about with your medical professional. You could also use it as a starting platform for one’s own research.

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Mine is already online but even what you see there is not what you would see now (even better) Oh I’m so tempted but I’m gonna hold off on it. Let me just tell you… it would embarrass you. You seem to be so proud of your physique but I find it just OK.Pictures will be out soon enough in a couple of months because of a project I have in the works.