A fascinating thread pertaining to men with very elevated (outside the reference range) SHBG levels. In these cases they may need to run their TT numbers in that supra-range in order to get their free T levels into mid range. Note I didn’t cover this type of situation above and goes to show the individual needs of each patient. However, this situation is not the same as a guy with an SHBG of 35 nmol/L and who can predict each person’s blood work (Hct, blood pressure, systemic vascular resistance) will move as a function of free T levels (15, 25, vs 40 ng/dL)?
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