What is TRT and What is NOT TRT

[tareload]

@Madagascarspirit

On the topic of Testosterone dose, if the upper end healthy man produces 7mg/day endogenously then it’s well understood that 100mg/week of the Cypionate/Enanthate ester will be equivalent.

@readalot

Here’s the time vs testosterone plot for 70 mg testosterone cypionate (TC) per week (dosing intervals of once per week and twice per week). Wait a few weeks and you reach steady state. TC has a molecular weight (MW) of 412.605 g/mol. Testosterone has MW of 288.42 g/mol. Hence TC is 69.9% testosterone by weight and 70 mg/week of TC is 49 mg/week of testosterone.

Just wanted to clarify…7 mg/day of testosterone is 49 mg/week of testosterone which would be equivalent to ~70 mg/week of testosterone cypionate. Testosterone enanthate MW is 400.603 g/mol so 49 mg/week of testosterone would be ~68 mg/week of testosterone enanthate. They are pretty close.

@Madagascarspirit

dubious ethical justification for conducting practices that don’t hold up well to scrutiny, logic or even general common sense.

To your point, 70-100 mg/week of testosterone ester would be generously equivalent to what top-quartile eugonadal healthy male is producing endogenously.

And guess what? When you go to the trouble on putting the dose response graphs together based on statistical meaningful samples of males taking exogenous testosterone, guess what you find?

Log-scale ordinate with highpull’s sample:

linear ordinate scale:

100 mg/week of exogenous testosterone ester puts 95%+ either at or above the physiologic reference range (and I was generous at the top end using 300 ng/dl up to 1200 ng/dl).

But of course using math, logic, human physiology, pharmacokinetics (ya know, science and such) profiteth little when discussing all this with the TOT apologists.

@tareload

Given we know nothing about you the responsible estimate for suggested starting dosage per week would be 75-100 mg/week of test ester. No, not a starting dose of 150 mg/week and no not a starting dose of 200 mg/week.

@enackers

That is a baby dose.

@enackers

My wife takes 50 and you want a male to take only twice that of a female?

@enackers

Just stop the nonsense. You have literally no clue what you are doing if you think 150 is a high dose.

@enackers

I guarantee you that the majority of folks on this forum would agree that 150 to 175 is just about what everyone takes at minimum

@enackers

Great. good for you. you can post a bunch of charts and shit. but you have zero clinical experience, which my source has.

Etc, etc, etc.

@dbossa

Try this: take 7mg a day. Once you have sufficiently chemically castrated yourself (which will occur quickly) you will quickly realize that you cannot compare endogenous and exogenous T. You’re also not factoring in androgen resistance which cannot be quantified using any unit of measurement. This is why the numbers are often meaningless when trying to resolve symptoms.

@enackers

Great. good for you. you can post a bunch of charts and shit. but you have zero clinical experience, which my source has. Who works direclty with Dr. Rouzier, who is the lead educator of HRT for men and women. Even the guys who give AI, put on their website they went to his clinics.

This Dr Rouzier will also backup my statements that your 100mg is not a normal dose for men.

If you are bored you can read this thread from beginning to end and find it is a decent compendium of logical fallacies. In fact any of you Philosophy 241 professors (bless you by the way) out there (@bkb333 not sure what you are a Professor of but don’t tell on here, keep you identity secret) feel free to use this thread for your class materials. Stay safe out there.