T Nation

what about 4-hydroxyisoleucine?

will it be good for upping the insulin spike in the PW meal with less high GI carbs while cutting?

should I cut the high GI carbs?

if not, is it good for anything else?



I was contemplating the exact same question the other day. I know that it is what is in EAS Insuload and that claims to elevate insulin levels, also I know they put it in Phosphagen XT for better creatine transport. Does anyone have any thoughts on this?

I’ve tried it.

In terms of recovery ALA is just as good, if glycogen replenishment is yo’ thang.

4HL, howvever, would be superior to ALA when low carbing, as it allows you to eat around 50g of C and still get a nice insulin spike. So the studies say anyway.

I’ve heard from someone that 4-hydroxyisoleucine, which comes from the herb Fenugreek, is actually quite an estrogenic compound there. The idea also is that since it promotes an insulin spike, along with the carbohydrates goes the phytoestrogens. I don’t know of the validity of this information since the person in question is an anti-estrogen fanatic, but I’d rather just stick with Alpha Lipoic Acid instead. At least I know that it works in terms of shuttling the right nutrients when it counts.