Yes, what you're using on a ME day should be a variation of the main lift unless you are testing out. Say on a ME Upper day you utilize a floor press one week, then a board press the next, close grip the next, etc.
PROGRAMMING SUGGESTIONS BELOW IS JUST MY TAKE ON CONJUGATE, MAY NOT WORK FOR YOU, THE DEFINITION OF ME AND DE STAY THE SAME HOWEVER
ME for both lower and upper is a variation of the main lift to a max single, double, or triple. That ME is followed by a few working sets in the chosen variation at a percentage of the ME, as well as a few accessory movements, which could be 2-3 on ME day that target your weak points. ME lower cycles weekly, with one week being deadlifts, and the other squats.
DE day for both lower and upper generally denotes three week waves where one variation is chosen to be worked against some form of accommodating resistance as explosively and quickly as possible (this variation is generally chosen to work a weak point) with each week the percentages getting heavier and the volume on the main movement lessening. The bulk of your hypertrophy assistance work is generally done on DE day, not all of it, but a good chunk.
Again, I'm just explaining my take on conjugate, there are many sources to look for good information from, notable ones being Elite FTS, as well as a tutorial series posted on the Massthetics YouTube channel (it's in a playlist).