Wise Guy wrote:
Dude, without a little more medical history, I can’t even begin to pontificate on this list.
For example, what type of depression/psychological problem do you have? If your Bi-Polar, or have periods of mania, there are quite a few supps on that list you shouldn’t take.
3g of DMAE is a ton man, a ton. Then you follow it up with more choline - Why? You are already juiced up with enough choline as it is with the DMAE.
I would keep that pira at 4.8g a day no more. No need for that extra serving.
Is that wellbutrin the extended release kind?
I appreciate your response. It’s funny that you should strive to pontificate on any subject as if that were a desirable thing. Besides that, my “psychological problem” is not bipolarity or mania in nature. It’s fairly straightforward “clinical depression”. I realize that 3g of DMAE appears to be alot. Most literature suggests a gradual increase on dosage with time. I’ve been taking it for about three years, with a lot of success, and increasing dosage steadily when I notice dulled effects.
As for your comment about DMAE and Choline, I’m afraid you are poorly misinformed. To put it briefly, it appears that in the end, DMAE may inhibit choline. In fact, Choline is recommended to be taken WITH DMAE to balance this effect out.
“Another reputed effect of DMAE supplementation is a rise in choline and acetylcholine levels and a corresponding increase in memory ability. This is based on the assumption that DMAE is a choline precursor and also crosses the blood brain barrier more effectively than choline itself , giving it the ability to reach the brain and then increase brain choline levels. DMAE does consistently increase levels of free choline in the brain and body, but this is not because it is a converted to choline ? it is because it competitively inhibits choline kinase and choline oxidase, preventing the metabolism of choline to phosphocholine and betaine. As mentioned above, this results in the production of phosphatidyl-DMAE. However, this is not necessarily beneficial, since it replaces phosphatidylcholine, and thus may effectively blunt some of the biological actions of phosphatidylcholine.” – 1fast400.com
Finally, unless your suggestion of taking less piracetam is based upon the amount of other supplements in my regimen, i’m not sure where you’re coming from: the recommended dose for Piracetam is 2.4g 3-4 times daily.
I’m not being aimlessly disagreeable here, just trying to make sure that my supplementation is optimal. I do appreciate you taking the time to respond.
You are being aimlessly disagreeable
Not only that, your sources are coming straight from the manufacture themselves - 1fast400, a large manufacturer of choline products.
Do a little more research on DMAE and you will find otherwise. I suggest you stay away from supplement company backed statements, LOL.
Your also basing your dosing recommendations for Pira off of that same company as well.
I base mine off a much, much more credible source - Life Extensions updated disease prevention manual, which basis its pira dosing off of European clinical research, were pira is prescribed quite often to treat a whole host of diseases.
Either way, I sense a lot of anger in you (typical of depression - anger turned inward), so I’m not wasting any more time arguing.