I probably should have been more clear. My thoughts and comments were based on my plans of wearing one all day.
I still would not recommend wearing a weight vest at your stand up desk 3-4 hours a day. Instead I would recommend wearing a weight vest every day you go on a long walk, do plyometrics, do sprint work(really I would suggest a small parachute here, or if you have a workout partner have them attached to you with a bungee cord rope), etc. I don't know man, I just don't like the idea of wearing one when you're not working out.