[quote]Peter Orban wrote:
If you mean 60-80 nmol/L, that equates to around 24-32 ng/mL, so I would have to say that such a small difference is negligible. CRP is not solely a measure of inflammation. Mild inflammation is 1-4 mg/dL CRP, well beyond the range expected by the study if one was to supplement 2000-4000 IU/d. Also the study was for asymptomatic people, so how this relates to disease is very unclear. Studies linking CRP to whatever are all over the map.
If anything CRP is more of a lagging indicator. When one looks at the variability of CRP levels in a group of test subjects in diseased and non-diseased states, it is quite large with great overlap between the two groups, thus the predictive nature of measuring one person’s CRP level at a given time is unclear. One would need a series of measurements for that person over time to make any correlation to a given disease or heightened risk.
Vitamin D intake that results in levels of 60-80 nmol/L has shown decreased mortality from all causes (by all it is meant in aggregate, not in every possible case).
I guess that is the long way of saying that there is more going on here.[/quote]
Agree with what you said but I’m pretty sure jehova meant 60-80 ng/ml
For example Dr. Oz recommends 50 ng/ml . Mercola and other recommend 50/60-80 ng
Yes, they do.
Regarding those suggestions, I propose that those doses need not be maintained indefinitely as I see a cyclical approach to be more “normal”. In my estimation, levels need only meet a threshold of 35-40 in the winter time (2-4000IUs with a meal containing fat will get most there), and in sunshiny times, a lower dose, or no dose at all, of natural sun exposure to bring a person up to 50-80 (higher pending serious disease state). Following and testing D levels twice yearly will potentially reveal vit D issues, disease state, indicate malabsorption of certain minerals, &/or fluctuations may otherwise reveal unhealthy change in lifesstyle, diet, etc. including dietary changes including removing lectin containing foods from the diet, as people with first diagnosed celiac disease most often have deficient blood levels of vit D3. Supplemental zinc, magnesium, selenium, and boron (which is sometimes hard to find – not at the grocery store usually) along with dairy calcium and exercise (to reduce excess body fat, which affects vit D storage) may help when supplemention alone does not change levels, or moderate doses do not have intended effect. Dairy calcium preferably from raw (organic) dairy from a trusted source.