Thought I’d post this here also to see if we can get a discussion going.
Anyone using this post workout?
It is supposed to enhance glycogen repletion in muscle cells after exercise by retarding glycolysis (aerobic glycolysis I think) by means of the inhibition of an enzime called phosphofructokinase.
There have been many people in other forums reporting changes in body composition while having higher carbs intakes, inclusively losing fat without that flat muscle look you tend to get with lower carb diets.
The active substance is acetic acid, and citric acid has been used in other studies with similar effects.
And here’s the abstract:
Acetic Acid Feeding Enhances Glycogen Repletion in Liver and Skeletal Muscle of Rats1
Takashi Fushimi2, Kenji Tayama, Masahiro Fukaya, Kaori Kitakoshi*, Naoya Nakai*, Yoshinori Tsukamoto and Yuzo Sato*
To investigate the efficacy of the ingestion of vinegar in aiding recovery from fatigue, we examined the effect of dietary acetic acid, the main component of vinegar, on glycogen repletion in rats. Rats were allowed access to a commercial diet twice daily for 6 d. After 15 h of food deprivation, they were either killed immediately or given 2 g of a diet containing 0 (control), 0.1, 0.2 or 0.4 g acetic acid/100 g diet for 2 h. The 0.2 g acetic acid group had significantly greater liver and gastrocnemius muscle glycogen concentration than the control group (P < 0.05). The concentrations of citrate in this group in both the liver and skeletal muscles were >1.3-fold greater than in the control group (P > 0.1). In liver, the concentration of xylulose-5-phosphate in the control group was significantly higher than in the 0.2 and 0.4 g acetic acid groups (P < 0.01). In gastrocnemius muscle, the concentration of glucose-6-phosphate in the control group was significantly lower and the ratio of fructose-1,6-bisphosphate/fructose-6-phosphate was significantly higher than in the 0.2 g acetic acid group (P < 0.05). This ratio in the soleus muscle of the acetic acid fed groups was <0.8-fold that of the control group (P > 0.1). In liver, acetic acid may activate gluconeogenesis and inactivate glycolysis through inactivation of fructose-2,6-bisphosphate synthesis due to suppression of xylulose-5-phosphate accumulation. In skeletal muscle, acetic acid may inhibit glycolysis by suppression of phosphofructokinase-1 activity. We conclude that a diet containing acetic acid may enhance glycogen repletion in liver and skeletal muscle.