Set realistic therapeutic goals. High normal TT, FT and E2=22pgml
Inject twice a week or EOD
Do labs half way between
Adjust doses as needed.
If you get E2=28pg/ml, to get near E2=22pg/ml, new dose = old dose x 28/22
I found that I need less anastrozole over the years. My doc says he has seen this before, so there can be some drift.