T Nation

Very Worried About My E2


Hello everyone, so long story short, I decided to go on trt due to some symptoms I was experiencing. My doctor prescribed me a testosterone gel, I applied it for 2 days before quiting. On both days I had bad panic attacks 2 hours after application. After some research I found out that my e2 could be very high. This is likely because of my very low SHBG (13.3), in addition my libido has completely gone. I have put this down to a high e2. I have decided to stop trt because in hindsight I may I have not needed it. However a few days after stopping I still have lost my libido, does anyone know how long it takes for the body to get rid of excess e2.
Thanks for your help


It’s extremely difficult to troubleshoot without labs, my doctor put me on too much test and I felt exactly the same. Blood pressure and increased heart rate dropped after lowering my dose, transdermals are crap!


Thanks for the reply, I’ve been off the gel for a few days but my libido is still dead and I feel weak. Hoping that my e2 is back to baseline in the next few weeks


It could take months to start feeling better after your on a more reasonable protocol. Once you start TRT your natural production is shut down, ask for injections no less than once a week injections (recommend. twice weekly), otherwise you feel like garbage at the middle of the second week.


I’m kind of worried that my estradiol will never lower to baseline, any other responses?


You don’t even know if you have an estradiol issue, it’s pointless to guess. Estradiol doesn’t rise so quickly to above normal ranges in just 2 days, you need labs to be able to interpret what’s going on.


With transdermals, estradiol can rise quite rapidly, assuming that my estradiol is high, how long do you think it could take to return to normal without using an AI, thanks for your response


We need your labs, not just sex hormones, with ranges and more info about you.

Please read the stickies found here: About the T Replacement Category

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.