Sorry for delay, all. Let me answer those questions.
Davidm: Bedtime injections mainly for convenience; pinning every day, I don't think time of day makes much difference.
-I am using the larger 25 syringes. I know, I should switch. Old habits...
-Anastrozole seemed to cause problems for me. Tried different doses, monitored E2, and regardless of the lab number, I usually felt like garbage, even when E2=22. Completely different story with Exemestane purchased from the same RC company.
-I would change one variable at a time, kept a daily log of symptoms/progress or lack thereof.
-The daily pins and high Exemestane dose are unusual, but I believe I tried just about everything else.
-My last SHBG reading was 15.7 (ref 16.5-55.9). Just below range.
-I am doing a couple dietary things to bring it up (green tea, increased fiber). I've not re-checked SHBG level since implementing those. Admittedly, there's less urgency to spend time and money on lab work when you're feeling good.
-Previous protocols (starting from ground zero ignorance, with a helpful but minimally knowledgeable general practitioner):
1x/week injections (100mg T Cyp) with no AI
2x/week (50mg) with no AI
3x/week injections (various doses) with no AI
These all produced rollercoaster good then bad days, mostly bad. Then added Anastrozole at various doses -- never felt particularly good, and sometimes felt absolutely horrible. (I can now sympathize much more with women with PMS.) Exemestane changed everything. After switching to daily T injections and a low dose of exemestane, everything was going well except no morning wood. Bit the bullet and jacked up the exemestane, and then that last missing piece got a lot better. Morning/nocturnal wood is still not completely consistent, but I can perform in the sack better at age 41 than I could at 35, which is the main goal.
I've never used HCG, mostly due to the cost. Everything I'm doing is out-of-pocket.
-I would usually try to run a protocol for at least a month to let things settle out, but I often felt so bad that I would be compelled to switch it up sooner than that.