Myth #10 of the The Top 10 Post Workout Nutrition Myths by Dave Barr.
"10. Aspirin and ibuprofen are good anti-inflammatories for muscle recovery.
The topic of muscle inflammation is pretty hot these days because it?s thought that minimizing this natural response will enhance recovery. By allowing us to hit the gym or get back on the field quicker, we can once again stimulate our bodies with a hard training session.
While the theory holds some water, we need to be careful how far we take it. For example, the use of traditional pain relievers, like aspirin and ibuprofen, has been increasingly common, because most people just don?t like the feeling of muscle soreness (T-Nation readers excepted because we?re hardly “most people”).
A common effect of these pain relievers is that they exert a powerful anti-inflammatory effect. This fact has excited some budding pseudo-scientists, because they reason that using these common drugs will reduce muscle inflammation and enhance recovery. Great theory, poor applicability.
Early research showed that post workout use of these drugs inhibited our natural production of a chemical necessary for muscle growth and repair (Trappe et al., 2001). Further investigation showed that sure enough, muscle protein synthesis was completely shut down when these drugs were combined with strength training (Trappe et al., 2002). As a final kick in the teeth, using these drugs resulted in no effect on either inflammation (Peterson et al., 2003), or muscle soreness (Trappe et al., 2002).
Essentially we get the worst of all worlds when combining nonsteroidal anti-inflammatory drugs (NSAIDS) like aspirin and ibuprofen, with strength straining. Having said that, it is important to note that there are several different ways of affecting inflammation, some may be good, others are clearly bad. Keep in the back of your mind that limiting inflammation is a good idea, but certainly be aware that it is not universally beneficial."