T Nation

TRT Injection Frequency


#1

Does anyone do ED injections with Test prop E OR CYP with slin pin? If so do you notice any benefit to that opposed to injecting 2x a week in terms of estrogen conversion/water retention,strength in gym , energy level etc ? Thanks


#2

yes

Please see these stickies:

  • advice for new guys
  • protocol for injections

#3

[quote]Squat79 wrote:
Does anyone do ED injections with Test prop E OR CYP with slin pin? If so do you notice any benefit to that opposed to injecting 2x a week in terms of estrogen conversion/water retention,strength in gym , energy level etc ? Thanks[/quote]

Your question doesn’t make sense. You can do twice per week injections with an insulin syringe or intramuscular syringes.

There has been no difference for me with twice per week or weekly injections with anything. And if one is on the proper dose of TRT there shouldn’t be water retention and high estradiol values.

I highly doubt there are discernible changes in feelings of well being from day to day on weekly injections, even if one went from say, T values of 1000 ng on a Sunday and down to 500 or so on Saturday.

There are no changes in strength in the gym while still being in the normal range. TRT doesn’t produce what can’t be achieved with normal T levels naturally.


#4

“And if one is on the proper dose of TRT there shouldn’t be water retention and high estradiol values.”

As a generalization I agree with you Brick, although if someone has a higher body fat percentage, aromatization of T -> E would likely be higher and could possibly induce higher e2 levels as a result.


#5

I’m aware that you can use either kind of pin…That doesn’t mean my question doesn’t make sense .It means I’d like to know if ppl are using slin pins for more frequent injections and what effects they had…There are many aspects regarding TRT and its effects yet to be understood such as coming closer to mimicking natural pulsatile release patterns and what effect that has compared to bigger doses spread out over time but thanks for your contribution.


#6

ED is not needed. The slow release action means that there will not be the pulses that you seek to mimic.

EOD is quite steady and many do this. This allows for proper balance of serum T and serum anastrozole levels. hCG can also be injected at the same time.

Twice a week and anastrozole at that time can work well, but does then hCG EOD becomes a very difficult routine.

Once a week creates high T peaks that promote higher E2 levels and T crashes make most feel like crap at the end of the week.

You would know this from the stickies.


#7

Is there any difference in estrogen conversion between quicker release test prop and slower release test Enan or Cyp ? Thanks


#8

We have evidence that smoother T levels produce less T–>E2 than spikier T levels. So a slower acting T ester would be marginally better. More frequent injections with overlapping release curves is the objective.


#9

Is there any truth to SC injections equating to a smoother release as in less peaks and valleys/ estro conversion than IM?


#10

Yes, the T is release slower. And T peaks can drive more T–>E2 than steadier levels.
With EOD injections, IM would also be very smooth. Might make a difference for twice a week dosing.

When injecting often, the main advantage of SC over IM is elimination of decades of muscle damage. Some get lumps with SC on legs and not into belly fat. Some vice versa. So do whatever makes life easier for you.


#11

Thanks…Do u see a need to supplement with pregnenolone and DHEA along with TRT protocol?


#12

If serum pregnenolone or DHEA-S labs are lowish.


#13

Does HCG increase cortisol ?


#14

I disagree about the TRT part not achieving beyond normal gains at the gym. Most TRT programs are going to put men in the optimal upper range which very few people have. The gym gains are phenomenal for me. I have been training and competing in local competitions for 18 years. Now that I am on TRT my levels are kissing the top range and my strength/physique at 34 is better than it was in my early 20s.

Note: I did not start TRT for this aspect. I started due to diagnosed hypogonadism by multiple specialist that I don’t believe I had as severe when I was younger.


#15

-not unless labs show you are low

No, why would a replacement dose for LH do that? Do young normal males have a high cortisol problem?


#16

How can one achieve beyond normal gains with T in the normal range? This makes no physiological sense.


#17

well i dont know…if you use a trt dose of test that is injecting 50- 100 mg into system at once which could increase test-cortisol ratio in a way that natural test release does not…then when u inject hcg that cortisol which has been lowered with test injection goes up…???


#18

I believe its a matter of what we are interpreting as ‘normal’. I suppose we are just looking at it from different perspectives. Consider… at every gym there is ‘that guy’ who always puts on muscle easier than the others. Anabolic users aside of course. Guys with ‘normal’ T ranges don’t do that. TRT users typically are experiencing the highest T levels in the ‘normal’ range giving them the ability to build muscle beyond the normal guy and more like those that are gifted naturally. So… no not supra-physiological but better than normal.


#19

.2 in a slin pin 5 days a week =250 mg a week.
Main reason is I felt more stable.
Second reason is I like to pin. And I keep track of dosing better.