Your question doesn't make sense. You can do twice per week injections with an insulin syringe or intramuscular syringes.
There has been no difference for me with twice per week or weekly injections with anything. And if one is on the proper dose of TRT there shouldn't be water retention and high estradiol values.
I highly doubt there are discernible changes in feelings of well being from day to day on weekly injections, even if one went from say, T values of 1000 ng on a Sunday and down to 500 or so on Saturday.
There are no changes in strength in the gym while still being in the normal range. TRT doesn't produce what can't be achieved with normal T levels naturally.