I may now have an answer to why I have had fatigue, weak to non-existent erections and libido on TRT except for the first couple of weeks. My doctors at Kaiser are not concerned at all. When I look at the symptoms of iron overload mimics low testosterone.
I’m also experiencing extreme confusion and fatigue like I have never experienced before, metal taste in my mouth and louding ringing in my ears. I’ll bet my red burning itchy skin problem is related, my liver must be overloaded with iron. My abdomen swells up on occasion.
Chronic cough = iron overload.
Burning itching skin = iron overload.
Acid reflux = iron overload.
Tests right at the start of TRT over 2 years ago:
Iron = 61 mcg/dL - 59 - 158 mcg/dL
Total iron binding capacity 425 mcg/dL - 250 - 425 mcg/dL
Iron saturation 14 % - 20 - 50 %
Iron labs as of now:
Iron = 395 mcg/dL - 59 - 158 mcg/dL
Total iron binding capacity 543 mcg/dL mcg/dL - 250 - 425 mcg/dL
Iron saturation 73 % - 20 - 50 %
Ferritin 35 ng/mL 25 - 336 ng/mL
I hope Defy Medical has an answer.
Iron overload can manifest as fatigue, joint pain, liver disease, heart disease, hypogonadism, diabetes mellitus and skin pigmentation (bronze skin).
Seven patients with varying psychiatric disorders were found to have iron overload as manifested by abnormal serum ferritin, transferrin saturation index (TSI), or excessive urinary iron. All possible sources of secondary iron overload were ruled out.
The patients were treated with the specific iron chelator, deferoxamine, given IM for seven to 22 weeks which resulted in significant clinical improvements. These cases indicate a need to be aware that disordered iron metabolism is a somatic cause of psychiatric illness and that there is clinical improvement upon lowering elevated iron levels in patients with iron overload.
Disturbances in iron metabolism can be genetic or acquired and accordingly manifest as primary or secondary iron overload state. Organ damage may result from iron overload and manifest clinically as cirrhosis, diabetes mellitus, arthritis, endocrine abnormalities and cardiomyopathy.
I now may have a reason for my hypogonadism.