T Nation

TRT and Drug Testing


If one is on TRT and wants to pass a drug test for athletic competition (CrossFit), how would this be accomplished? The scenario would be an athlete over age 50 undergoing TRT to raise low T up to around 900.

Anastrozole is definitely a banned substance and Clomid would indicate therapy in a blood test - the athlete would be using both with TRT.

Thanks in advance for your help!


What are the parameters for the test? Do you know what they are looking for? Elevated Total Test, T/E (testosterone to epitestosterone) ratio? Clearly if your using a banned substance they will find it, but doctor prescribed TRT shouldn’t be an issue, unless they consider your TT of 900 to be high. Which could be the case, the upper limit( for testing) at the VA is 850, and ive seen it around that number (800-900).


Just found this in their stated policy: https://s3.amazonaws.com/crossfitpubliccontent/2017CrossFitGames_DrugTestingProgram.pdf

Note: A Therapeutic Use Exemption for Hormone Replacement Therapy using anabolic substances will NOT be granted under any circumstance for either men or women. Therefore, any athlete who tests positive for any anabolic agents (e.g., testosterone), even if these anabolic agents are taken as part of medically supervised Hormone Replacement Therapy, will be disqualified from competition and subject to the appropriate sanctions as imposed by CrossFit Inc.

Looks like the only option is to cease TRT?


If you stop TRT, performance may negate the point of competition.

If you stay on TRT, you can still enjoy your athletic activities in a non competitive manner.


Found this regarding T/E. and Yes TRT can raise your T/E ratio. Normally it is somewhere around 1:1 in natty’s but can increase and anything over 6:1 is considered positive (mma testing). There is also another test they can do, called carbon isotope ratio (CIR) test which is designed to detect exogenous testosterone. So Yea, your only option would be to stop TRT, but then how do you compete?

“Usually, the amount of Testosterone (T) & Epitestosterone (E) are in similar proportions and their normal presence in urine has been found, on an average to be roughly equal to 1:1, although it varies on a case specific basis. In case any anabolic steroids or any related preparation is taken or if some pathological condition exists the testosterone level may increase while the epitestosterone levels tend to remain unaffected. Thus the overall T/E ratio is skewed from the normal values and as a result, T/E ratio tends to vary significantly from the normal in such cases. However, if an additional amount of epitestosterone is administered to such individuals, theoretically, it is capable to bring the skewed T/E ratio back to normal. As a result, epitestosterone is banned by many sporting authorities for being a potent masking agent for testosterone use, or rather abuse!”