Topical Methyl Testosterone

Is Methyl Testosterone liver toxic when applied topically?

yes, it’s the c17-aa alteration that makes the drug hepatotoxic. Whether it bypasses 1st pass effect or not may slightly mitigate hepatotoxicity, but it certainly doesn’t negate it

Otherwise injectable stanozolol wouldn’t be hepatotoxic either. Going by case reports and documented side effects in literature we can see that it clearly is.

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