It seems that the general consensus is to dose your AI on an EOD schedule to maintain steady E2 levels. After reading Dr. Crisler’s protocol for dosing HCG, I’m wondering if dosing your AI based on T=>E peaks would be of any benefit. I know one clinic that is using a E5D TRT protocol. Day 1: HCG. Day 2: 100mg test, 1mg Adex.
Does this make sense when you consider Adex half life and the timing of peak serum E2 levels? I’m not looking for a critique in specific clinic protocols, but rather some theories on timed doses based on peaks and half-lives rather than an EOD schedule.