[quote]Yo Momma wrote:
One of the many hallmarks of cancer cells is drug resistance, this disease is as individual in response as there are human beings.
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You said it!!! Very very very very true. There’s a delicate balance of using drugs to stop the cancerous cells with as little harm as possible to the human being. And one of the bigger problems with pharmaceuticals? Receptor specificity. Good example-- albuterol for asthma agonizing the beta receptors of the heart, thereby causing tachycardia as a side effect. Also, most drugs that human beings produce tend to also agonize receptors they were not intended to agonize, hence side effects and adverse effects.
Another good example is chemotheraputic agents meant to stop the life cycle of rapidly dividing cells (cancer cells), but at the same time halt other rapidly dividing cells of the body, such as the GI Tract (gi ulcerations, stomatitis, etc.), Hair Cells (hair loss) and blood cells (rbc’s-- anemia, wbc’s-- succeptablity to infection, platelets-- thrombocytopenia).
And immunosuppresants used in cancer therapy to adjuvate other medication therapies…they leave the person more resistant to infection and have a plethora of other undesireable side effects.
Not a perfect science by any means, and it’s not anyone’s fault, it’s that we as the human race are not there yet, we haven’t figured out better, more specific drugs or other mechanisms to diseases that have yet remained elusive to us.
And the problem with organ and bone marrow transplants? Histocompatability. The problem with surgery? Too many to name. Such is the inexact science of medicine…the human being is an extremely complex organism made up of extremely complex tisses, cells, chemical systems, enzyme systems, metabolic pathways, etc…etc…etc…
Who knows, the mechanism for a cure may be just under our noses? And what a great feat for science and the human race if we did find this in our lifetime!