I was curious if anyone out there has been on thermogenics(containing ephedra, caffeine, etc.) for extended periods of time and have noticed negative effects on mood or personality. I know that they can increase irritability, but I'm talking about serious mood swings, depression, anger, etc. I've been taking some form of thermo for probably 8 years with occasional breaks, but not nearly enough. I'm trying to determine if this could contribute to negative moods and attitude. Thanks for any input.