I'd put Jeb on the moderate to possibly even left side of the GOP spectrum, without sitting here and debating the minutia, but I agree that I don't see the party (and the country) willing to accept another Bush at this point. Hence, I'd wager that he won't survive the primary if he does run, and if he somehow does get the nomination via whatever miracle presents itself, then I do think his name will be a major, major liability in the general election.
As for Rand, I don't foresee him making it through the primary either. I just don't see a Tea Party candidate getting the nomination given where 2016 is going to present itself on some of the social and economic issues. I'd think the party is going to prefer a candidate that can appeal to swing voters, moderates, and even perhaps some 'blue dog' liberals.
I'll reiterate my comment in the previous thread from Pt. I of this thread. If a Republican is to get elected president, that candidate will need to run on a far more moderate to liberal social platform. Immigration, women's rights (including reproductive issues) and gay rights are defining issues that are shaping elections at the national level. The last few elections should have demonstrably shown this, and the cascading effect of social issues will continue to be exacerbated by the political clout of Generation Y (and later Generation Z) voters, who will be participating in greater numbers in the 2016 and 2020 elections and beyond, combined with the shifting attitudes of the late 20s - baby boomer populations on some of these issues too.