So, are you talking about any drug, or illegal narcotics, or...?
The whole drug thing amuses me, precisely because so many people freak out about it whilst not realizing that just about everyone in the modern world, including infants and toddlers, have taken drugs. If someone has popped some pseudoephedrine tablets for crapped up sinuses, they've taken drugs. If someone smokes cigarettes, they are addicted to a drug. If someone has every taken vicodin or codeine or morphine, etc, then they've taken drugs.
I've had people tell me I'm going to die for popping a caffeine tablet, and these same people drink the equivalent amount of caffeine in a Starbucks drink or energy 'shot'.
So, I'm all for 'most' drugs, as society really does depend on them in a number of ways. I take pseudoephedrine and caffeine responsibly on occasion when I need to drop my body fat low - in fact, I buy as much pseudoephedrine as I legally can each month, as I anticipate it eventually becoming prescription-only as people buy into hype.
I've drink alcohol recreationally, usually just a little wine though.
I've chewed morning glory seeds before to get the pretty visuals for a few minutes.
I chew tobacco on occasion.
I've tried a variety of legal highs.
I avoid illegal substances just because I can't risk the hassle of being caught and charged.
I do think some drugs 'bad', not as in evil, but as in too dangerous to risk. There's a difference between taking an ECA stack, for example, and taking meth. One can benefit you if used responsibly; the other can drag you into hell in short order if you're not careful.