A question: Why is that standard T injection protocols (e.g., 50mg cypionate 2x/wk, EOD or E3D schedules, or even the old once-per-week routine) do not take into account the half-life of the ester (cypionate = 8 days per the FDA)?
Running this protocol thru a calculator shows that you are quickly jacking T beyond normal ranges. Theoretically, this is because when you inject dose #2, much of dose #1 is still in your system; when you inject #3, much of #2 as well as some of #1 are still in your system, and so on. So both the peaks and valleys of T levels continue to increase until stabilizing at levels that would probably too high for most of us, other than perhaps the guys who are 6'5" and 300 lbs.
On one hand, that would explain why many guys who stick to a consistent, moderate regimen start off feeling pretty good but eventually get out of balance again (the T levels indicated above would lead to nasty E2, and next thing you know you're adjusting your T and AI dose to try to feel good again, and then the wheels come off the wagon). This is what I've faced more than once -- don't change a thing, be careful and methodical, and still eventually feel steadily crappier.
On the other hand, real-life blood work seems not to bear out the model above.
In any case, there has to be a reason this is not really on the radar. Any input is most appreciated.