Can you explain a little more man. I have low test so I got a script for this stuff from a cool doc. Why should i stay off of it>?
How do you cycle it?
What else do I need to know?
When you introduce T like that, the HPTA reduces the production from your tests. But transdermals lead to more T–>E aromatization in the skin. So E goes up, then SHBG goes up, your own T production drops even more and relative FT drops too and what TF you have then faces opposing action of E at the T receptors. In other words, you are screwed and will feel like crap. You would not want to cycle thatm but run away from it.
In general, you have to completely replace your own T production to increase T levels. An average health young male produces 10mg of T per week. If you absorb 10% of the T in a gel or creme (a good rule of thumb) then you would need to take 100mg transdermally just to break even.
Many do not absorb transdermals very well and it simply fails to work for those. For those who do well starting who need TRT, some will have skin changes and absorption will fall off. So for many who need TRT, transdermals are not the answer. [/quote]
The absorbion at the skin increases DHT conversion which decreases SHBG, which causes a quicker destruction of estrogen. I’ve been on it all, and am really surprised by your answer here KS. For many transdermals are not the answer, but for many it is. Most dosing is 50mg a day which is an absorbsion of 5mg a day or 35mg a week.
Which does fit nicely into the 4-7mg a day (28-49mg a week) production in the normal male. I prefer injections due to control and family issues, but fact is that transdermals lead to higher levels of DHT, Free Testosterone, Lower E levels and lower SHBG.