No problems. A common HCG protocol is 250iu twice weekly.
As for the Tren, many reccommend beginning with Tren Acetate so you can ease into it and get a feel for the side. I far prefer Tren Enanthate, and to be honest, most people that do have side with Tren still continue using despite them. Anxiety and Insomnia were very mild for me, even at 700mg Tren Ace + 400mg Test Prop weekly, and many here feel those sides could have been further mitigated by a slightly lower Test dosage (ie: 200-250mg weekly).
I may get flamed for this, but I'd just run enanthate, even if it is your first time, and have some prolactin control on hand. That way you can get away with injecting just quads and delts no problem.
If you do run Tren Acetate, you could use 2 sites on each quad with your delts (6 sites in total), and try pinning your triceps, glutes or lats occasionally to keep the rotation fresh.