The half life of a single injection of T, administered presumeably to a ‘normal male’, as the time have T levels increase then drop to 1/2 of the peak, relative to baseline… means what for TRT? The info sheet also states that the levels of FT are used to determine the half-life.
“and the free testosterone concentration will determine its half-life.”
“The half-life of … injected IM is approximately eight days”
The action of the liver determines the half-life and there can be differences and and changes to the action of the liver, also from other demands placed on the same enzyme pathways from alcohol and drugs. Liver disease/aging is also part of the picture.
If one feels crappy at the end of the week when injecting once a week, injecting twice a week [or more] will change things a lot. The differences between the esters will be of a lesser effect. A trial, injecting more often, will be value for any individual. There is a difference between theory and individual experience.
If E2 is not controlled, the outcome can be poor from that alone and tyring other esters or injection frequencies will not provide good responses. In that case, the main problem is estrogen and only dealing with that will yield significant results. Elevated estrogen trumps everything.
Edit: I have also seen figures quoted for half-life that are obviously a confusion with the clearance time or a return to baseline time frame. Once that gets posted, others read it and pass on that misunderstanding.