Drugs, Rx or OTC can create problems with the ability of the liver to clear estrogens from the body. That includes excess alcohol consumption. The poster child for this is a drug that is generic OTC in the USA - cimetidine for heart burn. There are more effective drugs and it should not exist in the market place. These problems can be resolved with alternate drugs or simply stopping the drug. But if the result is gyno, surgery may be required.
All drugs that one takes should be reviewed for potential endocrine disruption. Search for metabolic pathways for drugs that involve the P450 liver enzymes. Looks for drugs that increase prolactin as that is very HPTA repressive.
I see young guys with permanent hypogonadism from deca only and some PH use. That is probably compounded by no or stupid PCT. Same can occur for some who only use a 5-alpha reductase inhibitor for hair loss.
Some drugs may make some feel off peak temporarily. Some of you are destined for permanent damage with some of these bad actors. Some guys have a genetic makeup that produces a brittle HPTA. But who here does not have a "can't happen to me" attitude.
The PH market place makes me sick and embodies all of the shit that drives anti-steroid legislation. The situation proves that people have to be protected [from themselves]. My perspective is unique because young guys who are learning after the fact, find me, seeking a way out. I have not seen any of these young men return to any state of normalcy without a TRT end point.
The legislative pressures have no effect on the PH market place and only make life worse for those who seek intelligent informed steroid use. And we get doctors who are afraid to do TRT as part of the result.