There is far too much estrogen in Synovex to even consider this. Estrogen is highly potent, far moreso than testosterone… 1 mg/day is a full replacement dose for a woman! It is not easy to remove the estrogen from Synovex either and cannot, realistically speaking, be done with 100% removal anywhere except the laboratory. Lastly, the liver “issue” you raise, is a non-issue with non-17-alkylated steroids, and “cleaning” is not so far as I know an issue or realistic thing with those steroids either. Rather, one simply avoids overuse and has off periods. Some think milk thistle helps, and I’m not saying it doesn’t but I’m also saying I’m not convinced it does, but am convinced it is not necessary given the above precautions.