Omega-3's from fish oil have a lot of science behind them in regards to pain relief and inflammation reduction especially for chronic conditions. Curcumin is an extremely interesting substance and there's a lot of research going on right now regarding just how much this stuff will do -- not just for pain relief but as one of the 'must-have' supplements for prevention of some cancers and many other serious conditions. The information is still a bit young, and who knows what the longer term studies will say, but so far the information is very exciting. Anecdotal reports and personal experience indicate that the claims of acute pain relief are valid.
In fact, I think it's not unreasonable to say that there are dozens of reasons to take both of said supplements on a daily basis, and I know of no reasons to avoid them (unless enough studies along the line disprove curcumin's cancer fighting properties). And curcumin is a standardized extract of a component of turmeric...so unless you get brain fog from curry, I don't think you're going to have any problems in that department, even in high doses.