T Nation

Supplements That Increase IGF-1


Does anyone know any ways to increase IGF-1 rather than taking IGF-1? I foudn this interesting article that says that Capsaicin and Soy Isoflavones increase it and also increase hair growth. inhumanexperiment.blogspot.com/2009/09/capsaicin-and-soy-isoflavones-grow-hair.html

I'm wondering though if the soy isoflavones increase IGF-1 at the expense of Test.

I'm looking for a supplement to take to give a boost to several different hormones like GH and LH (agmatine for both and alpha gpc for GH at least), insulin (anaconda protocol), test (heavy lifting, Rez-V, TRIBEX). Obviously Gh will convert to IGF-1 a little bit, but a direct boost would be awesome.


I thought this would be relevant:



You'd be better off by training consistently to increase IGF-1.


Oh duh! Of course colostrum has IGF-1 in it! I knew that. The question with that though is whether it's enough in there to do anything.


Ran by an old Cy Wilson article on here which pointed out that colostrum did increase IGF-1 in athletes, but he also said that 5-methyl-7-methoxy-isoflavone was useful and it is not useful at all as many of us know too well.

also he said that capsaicin could be depleting glycogen stores while preserving fat stores :confused:

He also mentioned that coleus was a no go as was fenugreek. Both compounds are in current Biotest products, so I'm a little lost.




How do you know that? To what extent does training increase IGF-1? What type of training increases IGF-1 levels the most? I read through this very well put together study titled "Resistance exercise alters MRF and IGF-I mRNA content in human skeletal muscle" http://jap.physiology.org/cgi/content/full/95/3/1038 and it did not even seem to give these answers. If you do have the answers though, please share.

It did say though that

MRFs are a family of skeletal muscle-specific transcription factors that regulate the expression of several skeletal muscle genes

The study didn't give much in the way of recommendations relating to training style or recovery period to optimize the hormones responsible for hypertrophy. They did give this nice little graph though which shows hormonal levels at different points in time, but it doesn't tell me much:

So do you have the answers I was unable to find? If so please share them.