T Nation

Sugar: The Bitter Truth

After watching this, although the science may potentially be flawed (since he is comparing fructose to ethanol, like what the fuck?), which I highly doubt, it’s still something that is essential and important, and, differentiating between glucose and fructose is key.

Coles Notes please.

[quote]MementoMori wrote:
Coles Notes please.[/quote]

I posted this so other’s may see what this man has to say, not what I think of this lecture.

This was posted before in response to another thread. Definitely worth the time.

I’d say his science is most likely not flawed, but I’m not a biochemistry major (yet). Chemically, they aren’t all that different. Ethanol is processed in the brain, leading to intoxication; whereas sugar obviously isn’t, and doesn’t. But for most people, regardless of the alcohol comparison, this should be a major wake up call.

Americans (the 100 calorie cookie eaters, not T-Nation) are pretty dumb. I don’t really see the obsession with sugar. I’m making it top of my list things to quit, along with alcohol. Neither have ever done anything good for me.

[quote]ALA wrote:

After watching this, although the science may potentially be flawed (since he is comparing fructose to ethanol, like what the fuck?), which I highly doubt…

[/quote]

If you listened to what he was saying, you would understand. He’s a fucking endocrinologist, that shit’s up there with neurology as one of the absolute most difficult specialties in medicine. Sure, it’s really convenient to you that fructose doesn’t act like ethanol, but tough shit, it does.

Arguing with facts makes you seem really stupid.

who listened to the 90min? I sure didnt

[quote]Xab wrote:
Arguing with facts makes you seem really stupid. [/quote]

Calling someone stupid makes it seem like your facts are worthless. Just saying.

That video is over an hour long.

<---- Did not watch.

Just finished watching it. Was very informative though I’m willing to bet a good chunk of this site’s readers already have at least a passing idea of what was contained in the vid. I plan on sending it to some people as I know a few who just don’t believe me when I tell them their “lo-fat” ice cream isn’t magically healthy.

I just watched through it, was very interesting and informative.

Essentially, fructose is only metabolized by the liver, and by the same pathway as ethanol. Pure glucose is absorbed mostly by the body with only a small (1/5) ending up in the liver. It can then can be safely stored as glycogen in the liver for later use. Some is used for metabolism and then a very small excess if any is converted to fat- out of 120cal of glucose, 0.5 might end up as fat.

ALL fructose ends up in the liver, so the liver gets hit with 3 times as much carbohydrate from an equivalent quantity of glucose vs sugar. Since it can’t be stored as glycogen fructose ends up going straight into metabolism, where not being needed it turns into a huge excess of energy to be converted into fat, as well as increasing insulin and blocking hormones that signal that enough fat has been made. Out of 120cal of sugar, 60-70 end up as fat, just because of fructose.

He compares it to ethanol since they follow the same metabolic pathway- the reason beer makes you fat is identical to fructose, the liver ends up with a huge pile of extra calories it can’t store, and your brain doesn’t know and keeps thinking it’s hungry since it’s not getting lots of glycogen. Since fructose causes chronic problems and can only be metabolized by the liver, it also can fit the definition of poison.

[quote]Chris The Great wrote:
I just watched through it, was very interesting and informative.

Essentially, fructose is only metabolized by the liver, and by the same pathway as ethanol. Pure glucose is absorbed mostly by the body with only a small (1/5) ending up in the liver. It can then can be safely stored as glycogen in the liver for later use. Some is used for metabolism and then a very small excess if any is converted to fat- out of 120cal of glucose, 0.5 might end up as fat.

ALL fructose ends up in the liver, so the liver gets hit with 3 times as much carbohydrate from an equivalent quantity of glucose vs sugar. Since it can’t be stored as glycogen fructose ends up going straight into metabolism, where not being needed it turns into a huge excess of energy to be converted into fat, as well as increasing insulin and blocking hormones that signal that enough fat has been made. Out of 120cal of sugar, 60-70 end up as fat, just because of fructose.

He compares it to ethanol since they follow the same metabolic pathway- the reason beer makes you fat is identical to fructose, the liver ends up with a huge pile of extra calories it can’t store, and your brain doesn’t know and keeps thinking it’s hungry since it’s not getting lots of glycogen. Since fructose causes chronic problems and can only be metabolized by the liver, it also can fit the definition of poison.[/quote]

Good summary!

I apologise heartily in advance of my ignorance, but…

Are we talking about Fructose a.k.a Sugar from Fruit? or are we talking about High Fructose Corn Syrup and all it’s manmade artificial derivatives.

Somewhat confused.

Sec

[quote]Secutor84 wrote:
I apologise heartily in advance of my ignorance, but…

Are we talking about Fructose a.k.a Sugar from Fruit? or are we talking about High Fructose Corn Syrup and all it’s manmade artificial derivatives.

Somewhat confused.

Sec[/quote]

Both really:

Fructose = Fructose
HFCS = 45-55% Fructose
Fruit = Varies widely (>50% I believe)

The lecturer also mentioned that whole fruit isn’t really that evil, due to the fibre and phytonutrient content (The fructose would still be bad, but the benefits of fruit greatly outweigh the cost of the fruit’s fructose content)

So fructose, HFCS, sucrose are the cautionary sugars.

I enjoyed this presentation about how different sugars have unique metabolic pathways in the body. Makes me wonder why america is so obsessed with sweets and sugar and vilifies fat and protein. What is also interesting is how he talks of the effect exercise has on fat loss depend not so much on the calories burnt but on the hormonal and metabolic changes exercise does which seems to explain why complexes work so well. Btw one of my friends is a pediatric endocrinologist so I get some of what he is saying.

So, if I understand this correctly, natural fructose sources are ok (.e fruits), but processed fructose is not.

Could glucose be used instead of fructose?

I just did a search and found this:

Corn syrup: An inexpensive, clear, somewhat viscous syrup that is made from chemically refined cornstarch. Corn syrup is composed of at least 90 percent simple carbohydrates. In its purest form, it contains only glucose, but sucrose is usually added to bolster sweetness. Otherwise, its flavor is devoid of character.

http://findarticles.com/p/articles/mi_m0820/is_n214/ai_16930503/

  • I don’t think its debatable that high fructose corn syrup is bad for you, but is pure corn syrup acceptable since its almost pure glucose?

[quote]Bunyip wrote:
So, if I understand this correctly, natural fructose sources are ok (.e fruits), but processed fructose is not.

Could glucose be used instead of fructose?

[/quote]

Glucose can be used instead of fructose but fructose is sweeter than glucose, actually fructose is the sweetest of all naturally occurring carbohydrates, so the manufacturers with fructose get the best bang for their buck.

[quote]Bunyip wrote:
So, if I understand this correctly, natural fructose sources are ok (.e fruits), but processed fructose is not.

Could glucose be used instead of fructose?

[/quote]

Well, actually his argument is that all fructose is bad, period. The reason why fruits aren’t bad for you though has to do with the massive amounts of fiber as well as the vitamin content and the micronutrients. But even then, fruitarian diets suck, so “apple a day” and all that.

Very interesting video(yeah, I watched the whole thing). I’ve heard much of this stuff before, but never stressed in quite the same way. I’m not entirely sold on his premise(that fructose is as bad or worse than alcohol) but he certainly presents a cogent and thoughtful argument with data to support his claims. Would like to hear/read more on this topic.

I would think that pure corn syrup, which is mostly glucose (obviously you’ll need some careful label reading here!) would actually be great for a workout drink, since the glucose would go straight to your muscles when they need it. Might be something to look into?

Still it really lays out how bad fructose is in the quantities we ingest. Like 60lb a year or something like that for the US, of straight fructose from all sources. The more you learn about how our bodies handle food and what our food system throws at us the more obvious the whole disgustingly obese children thing comes from.

OTOH internet fatty threads are comedy gold imho