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Study: Increasing Curcumin's Anti-Inflammatory Activity


#1

Here is a study on this; there is another one I canâ??t find right now that used MCT and a 1% emulsion. That showed an increase of bioavailability of 83%. There are also studies on fish oils showing the same thing. This definitely point to the advantages of emulsions over taking the oil soluble straight.

It also point to using a "Oil Carrier" to dissolve the drug then emulsifying it works just as good. The trick is the drug has to soluble in the carrier enough so that when the particle size is reduced to a micelle it wonâ??t precipitate out. Oh yes other studies showed a correlation between emulsion droplet size and oral bioavailability. Basically the smaller it got the higher the bioavailability. Some got down to 100 nm.

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T25-4VT5TJC-1&_user=10&_coverDate=06%2F28%2F2009&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1692879612&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=336b127f575277fc2999ee4425ebc9ed&searchtype=a