T Nation

Struggling to Dial in TRT


Been on TRT for a year now, but I believe I’m having trouble dialing in e2.
First here are bloods.
This was my protocol during this blood test.
Test cyp 200mg/week split dose, HCG 1000iu/week split dose.

This was my first time having estrogen( I’ve had E2 checked before)checked and I was completely blown away with how high it was. At the time I had it checked I was not using Arimidex, as I had a bad experience the last time I used it thinking I went too low and just stayed away. I had bloods checked a year ago Test was at 975 (believe I was 4 weeks into TRT), free test 23, and E2 43. I’ve been having ED issues consistently and things have just started to get somewhat better, but still can’t go even 3 days straight with morning wood and flaccid definitely feels deflated most days which isn’t something Ive experienced. I have Cialis on hand and it works very effectively each time so I don’t believe I have any veinous leakage although not sure If that can be ruled out.

Currently I’m still on 200mg test cyp split into two shots a week (100mg on Tuesday and Friday). I have HCG on hand however I have recently gone off it. My goal was to eliminate as many factors that could effect estrogen. The first time I took HCG was 8 months ago. I was having excellent results on HCG by the 4th week doing two injection of 500iu every 3.5 days. HCG as of late was not having the same results. First time I took HCG provided increased penile sensitivity, testicular size maximized, and great erection quality. As of recent I was just getting a slight increase in testicular size.

I have arimidex on hand and truthfully think this is where I stumble with a proper protocol and reading my body when to take more. I am very careful not to overdue arimidex and don’t take more than 0.25mg in a single dose. I had been doing 0.25mg twice a week every 3.5 days.

I’m trying to figure out how things have changed in my body as as I used to compete and would cycle no more than 700mg a week total. I have only ever take Test cyp, enenthate, propionate, deca (6 years ago never again), and sustanon. I definitely have struggled with estrogen control this entire time and admit to being quite uneducated in regards to how to dial in hormones earlier on. Many of my cycles I have never had ED issues but little by little it has gotten worse.

1 year ago I could not get a strong erection(70%) but was able to orgasm normally multiple times a day. Now I am getting quite strong erections most days of the week, but am having trouble with libido, achieving orgasm, and flaccid size is smaller than its been in past. I’m seeing my Endo this week and he might not be the best but he certainly is very cautious and will provide scripts. Any insight into the issues I’m struggling with would be greatly appreciated as I’m not sure how to proceed moving forward.


This was taken on a trough day?

Why don’t you lower your testosterone dose to a “replacement” level instead of 1400. You will probably have a lot less issues with E2, if your test is in the 1000 range.


Bloods were taken on a Thursday so one day before next 100mg cyp.


Estrogen is way too high. I had the same issue but my doctor won’t give anything for it, so I cut my dosage. Overall your Total T and Free are too high for therapy. If I was you, I’d see how you felt on 140 divided twice a week instead of 200 and go from there. More is not always better.


Most need 1mg anastrozole per 100mg T ester.
Take 1mg at time of injections.

Your goal is E2=22pg/ml

A few, not rare and no way to know in advance, are anastrozole over-responders who need 1/4mg per 100mg T.

So you could start with 1/2mg at time of injections for a week, two doses and if you feel OK, not crashed, take 1mg with each injection.

A steady dose takes a week to get to final serum anastrozole levels. So no quick seat of the pants dose changes based on how you feel except for as suggested above.

There is no need to test total estrogens.

Most guys who come here have some degree of low thyroid function, often a result of not using iodized salt. Please eval via oral body temperatures as per below.

Please read the stickies found here: About the T Replacement Category

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re Thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number Aand ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.


If you want to get your TRT working right you will pay attention to all of the material provided above.

Describe your history of using iodized salt.
Post oral body temps for both times of day.

Please do not be a selective reader.

Keep your case in this one thread.


Hi KSman not sure how to start a new post or private mail.
Could you help on some information regarding low FSH 1-1.4 levels over severa bloods LH always 5-6 , test low - low normal over space of 1.5 years
Trying to gather information as getting various advice.