This is my first post here. I am a 31 year old male on 200 mg/week test. cypionate and arimidex every other day. I have been on TRT for about 7 months now.
I started feeling depression/anxiety symptoms along with low libido around 6-8 years ago (I was about 25 at the time) and they tested my hormones just to see if it was low testosterone related.
Here are pre trt labs done in 2014 -
Test total serum - 404 ng/dl
Test Free - 8.6 pg/ml
TSH - 1.520 uIU/mL
My cholesterol was high (total 237)
My glucose was slightly high at 102 mg/dl
Vitamin D low at 22.1 ng/ml
I went to an endo and he started me on androgel which at least noticeably increase sex drive but I went off of it not sure if I wanted to be on TRT forever at that point.
I continued to feel the negative symptoms so I went to a urologist who ended up putting me on 100 mg/biweekly test cypionate injected in the office. First week felt more irritated but slightly higher energy. After about 3 weeks I felt absolutely amazing - very high libido, life didnt feel worthless, interest in fun activities again, my anxiety was dramatically better. Thats how i felt about 4-5 days out of the two weeks before my next shot. After about three months they increased the dose to 200 mg/biweekly but I cant remember if that was the shot that stopped feeling like it did anything positive for me. I ended up moving to another state where I would temporarily lose my insurance so I stopped after that last shot that I felt no effects from.
Fast forward to about 10 months later I moved back CA where I was able to see my old urologist and he put me on 200 mg/biweekly. I waited for the 3-4 week change that relieved all my symptoms like before, but aside from a few good days here and there - it never came. After a few months the urologist increased my dose to 200 mg/weekly. These are the labs after it was increased to 200/weekly
Testosterone Total - 1417 ng/dl
free test - 43.9 pg/ml
estadiol - 64.2 pg/ml
This was taken around the peak day.
He then put me on arimidex every other day in addition to the 200 mg test cypionate per week. Here are most recent labs taken the day before shot after starting anastrozole every other day:
RBC high - 5.84 doctor said will test again in 2 months
Hematocrit high - 52.2
Total T - 1050
Estradiol - 13.3
I feel like about half the time now I feel slightly better but absolutely nothing like the few days every two week injection when I first started. Still relatively low libido, still depressed to the point of just staring at the wall because nothing sounds worth doing, and still high anxiety (though that is what has improved the most and what I feel change negatively the most towards the end of the week.
At this point I don’t know what the hell is going on, my doctor says with the high testosterone I should feel a high libido and he thinks its a depression issue not related to testosterone but the
depression/anxiety/libido/energy is why I went on TRT to begin with. I have occasionally tried experimenting with a lower dose but only for one week and went back due to anxiety increasing. Any recommendations would be greatly appreciated.