Oxandrolone - Anavar
Anavar was the old U.S. brand name for the oral steroid oxandrolone, first produced in 1964 by the drug manufacturer Searle. Oxandrolone will not aromatize, and therefore the anabolic effect of the compound can actually promote linear growth. Women usually tolerate this drug well at low doses, and at one time it was prescribed for the treatment of osteoporosis. Anavar is a mild anabolic with low androgenic activity. Anavars reduced androgenic activity has much to due with the fact that it is a derivative of dihydrotestosterone. Although you might think at first glance this would make it a more androgenic steroid, it in fact creates a steroid that is less androgenic because it is already “5-alpha reduced”. In other words, it lacks the capacity to interact with the 5-alpha reductase enzyme and convert to a more potent “di hydro” form. It is a simply matter of where a steroid is capable of being potentiated in the body, and with Anavar we do not have the same potential as testosterone, which is several times more active in androgen responsive tissues compared to muscle tissue due to its conversion to DHT. It essence oxandrolone has a balanced level of potency in both muscle and androgenic target tissues such as the scalp, skin and prostate. This is a similar situation as is noted with Primobolan Depot and Winstrol, which are also derived from dihydrotestosterone yet not known to be very androgenic substances.
Anavar is known as a good agent for the promotion of strength and quality muscle mass gains, although the mild nature of this compound makes it less than ideal for bulking purposes. Among bodybuilders Anavar is most commonly used during cutting phases of training when water retention is a concern.
Studies using low dosages of Anavar note minimal interferences with natural testosterone production. Likewise when it is used alone in small amounts there is typically no need for ancillary drugs like Clomid/ Nolvadex or hCG (Human Chorionic Gonadotropin). This has a lot to do with the fact that it does not convert to estrogen, which we know has an extremely profound effect on endogenous hormone production. Without estrogen to trigger negative feedback, we seem to note a higher threshold before inhibition is noted. But at higher dosages course, a suppression of natural testosterone levels will still occur with this drug as with any anabolic/androgenic steroid. This makes clear that while estrogen is important in this regard, androgen action triggers feedback inhibition as well, in the context of the average bodybuilder using Anavar at a level to promote growth, we would probably expect that maintaining a normal level of endogenous testosterone release would likewise be very difficult.
Anavar is also a 17 alpha alkylated oral steroid, carrying an alteration that is noted for putting stress on the liver. It is important to point out however that to spite this alteration Anavar is generally very well tolerated. While liver enzyme tests will occasionally show elevated values, actual damage due to this steroid is not a statistical problem. Bio-Technology General states that Anavar is not as extensively metabolized by the liver as other 17 aa orals are; evidenced by the fact that nearly a third of the compound is still intact when excreted in the urine. This may have to do with the understood milder nature of this agent (compared to other 17aa orals) in terms of heepatotoxicity. One study comparing the effects of Anavar to other agents including as Methyltestosterone, norethandrolone, Halotestin and methandriol clearly supports this notion. Here it was demonstrated that Anavar causes the lowest sulfobromophthalein (BSP; a marker of liver stress) retention among all the alkylated orals tested. 20 mg of oxandrolone in fact produced 72% less BSP retention than an equal dosage of Halotestin, which is a considerable difference being that they possess the same liver-toxic alteration. With such findings, combined with the fact that athletes rarely report trouble with this drug, most feel comfortable believing it to be much safer to use during longer cycles than most of other orals with this distinction. Although this may very well be true, the chance of liver damage still cannot be excluded however.
At one time Anavar was also looked at as a possible drug for those suffering from disorders of high cholesterol or triglycerides. Early studies showed it to be capable of lowering total cholesterol and triglyceride values in certain types of hyperlipidemic patients, which initially this was thought to signify potential for this drug as a hypo-lipid (lipid lowering) agent. With further investigation we find however that while use of Anavar can be linked to a lowering of total cholesterol values, it is such that a redistribution in the ratio of good (HDL) to bad (LDL) cholesterol occurs, usually moving values in an unfavorable direction. This would of course negate any positive effect that the drug might have on triglycerides or total cholesterol, and in fact make it a danger in terms of cardiac risk when taken for prolonged periods of time. Today we understand that as a group anabolic/androgenic steroids produce very unfavorable changes in lipid profiles, and are really not useful in disorders of lipid metabolism. As an oral c17 alpha alkylated steroid, Anavar is probably even more risky to use than an injectable esterified injectable such as a testosterone or nandrolone in this regard.
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Oxandrolone Side Effects
Altogugh Oxandrolone is nowhere near Halotestin or Anadrol in hepa-toxicity, it too is a 17-alpha-alkylated substance that can cause liver damage if used for long periods on end. Other common side-effects include headaches, loss of libido, diarrhea and dizziness.
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Oxandrolone Dosage
The standard dosage of Anavar for men is in the range of 15-25 mg (6-10 tablets) per day, a level that should produce noticeable results. It can be further combined with anabolics like Primobolan Depot and Winstrol to elicit a harder, more defined look without added water retention. Such combinations are very popular and can dramatically enhance the show physique. One can also add strong non-aromatizing androgens like Halotestin, Proviron or Trenbolone. In this case the androgen really helps to harden up the muscles, while at the same time making conditions more favorable for fat reduction. Some athletes do choose to incorporate Anavar into bulking stacks, but usually with standard bulking drugs like testosterone or Dianabol. The usual goal in this instance is an additional gain of strength, as well as more quality look to the androgen bulk. Women who fear the masculinizing effects of many steroids would be quite comfortable using this drug, as this is very rarely seen with low doses. Here a daily dosage for Oxandrolone is 5 mg, this should illicit considerable growth without the noticeable androgenic side effects of other drugs. Eager females may wish to addition mild anabolics like Winstrol, Primobolan Depot or Durabolin. When combined with such anabolic steroids, the user should notice faster, more pronounced muscle building effects, but may also increase the likelihood of androgenic buildup.
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Oxandrolone Alternative Names
* Oxanadrolic
* Oxanabol
* Oxanol
* Oxandrolone Paper
* Anavar or Anatrophill or Lipidex or Lonavar
* Lonavar
* Oxandrolone
* Vasorome
* Oxandrolone
* Oxandrin (US)
Oxandrolone Half-Life and Detection Time
Oxandrolone half-life is 9 hours.
Oxandrolone detection time is around 3 weeks…