Starting Anti-Depressants on TRT?

Your protocol is to blame for your problems on TRT, 40mg weekly isn’t a good protocol at all especially if SHBG is low. Your protocol is so far off the mark of what’s considered standard practice. Most men are closer to 100mg weekly, I’m at 92mg weekly split up every 2 days. You may do better on multiple smaller injections per week.

I have no depression or anxiety and even I get a little moody on new protocols, however as I get closer to 6 weeks if levels are elevated 24/7 and not just a few days out of the week, I feel the fluctuations simmer down.

We talked about getting SHBG tested and how your doctor thought it was a good idea to start TRT blindfolded. Suggest finding a competent doctors.

The men who start TRT with experience doctors seem to have the least problems and those who startout with inexperienced doctors seem to be the ones struggling the most.