T Nation

Splitting up

Considering half lives and blood concentration levels might it be a good idea to split up “M” Doses? IE: 2 capsules in the morning and 1 at night?

I think you are on to something-I will try it and see if it works better it should-higher more consistant blood levels!

I used to think that taking vitex or M at night would be a good idea and I did so. However, it caused me to wake up in the morning feeling nausea and my sex drive diminished. Then I tried M in the morning as directed and I felt great with an increase in sex drive. This did not make sense to me until I read Lyle McDonald’s book on Bromocriptine. Bromocriptine like Vitex is a dopamine D2 agonist. Dopamine is high in the evening and low in the morning. If you take Bromo or Vitex in the morning you will be fine because dopamine is low. However, if you take them in the evening it may cause too much activation of the dopamine receptor and may lead to adverse affects affilliated with too much dopaminergic tone. For those who have not read Lyle’s book I would recommend it. I would theorize that Vitex or M taken in the morning like Bromocriptine would have positive effects on fat loss during caloric restriction.

Interesting stuff bud, thanks!..