Manufacturers claim on their website that Splenda is not metabolized or absorbed, and this is completely false! It is true that the majority of sucralose that is consumed is excreted in the feces and urine unchanged, but the reality is that up to 40% of the ingested sucralose is metabolized. Both the metabolites and unchanged absorbed sucralose are excreted in the urine. Meanwhile, absorbed sucralose has been found to concentrate in the liver, kidney and GI tract. The Sucralose Toxicity Information Center has also found that sucralose breaks down into small amounts of 1,6-dichlorofructose, which is a chemical that has not been tested adequately in humans.
Because sucralose is a chlorinated molecule, when metabolized, some of the chlorine and other substances in splenda (including arsenic, or rat poison) is taken by the system. Alarming? Yes, when we realize that chlorinated molecules serve as the basis for pesticides like DDT and accumulate in body fat.
According to the FDA report, ?Results from the submitted animal and human pharmacokinetics data identified three major sucralosemetabolites (Ml, M2, and M3) in urine in addition to unchanged sucralose.? The report also states, ?The metabolic profile of sucralose in rats was qualitatively similar to that seen in humans. In addition to unchanged sucralose, two sucralose metabolites, Ml and M2, were detected in the urine of rats and humans after oral dosing of sucralose?A pronounced difference was observed in the proportions of M2 and M3 excreted by male versus female mice: Males produced more M2 than M3, while the opposite was true of female mice.? Even within FDA and industry studies, metabolization and absorption of Splen-da is shown; why are the manufacturers claiming that it is not? What else are they claiming that is not true? What are they hiding?