I’ve only been reading non-peer reviewed anecdotes about how men with low SHBG do not benefit from TRT (in terms of sexual function). I’ve also heard that a lot of low testosterone issues are caused in part by low SHBG, as this binds with compounds found in modern foods and plastics.
I personally have low SHBG, in fact this is the primary reason no endocrinologists never wanted to work with me as the mantra is low SHBG means more testosterone! Yay right? Well no, apparently it’s a pretty serious issue for men. Mine have been as low as 8 (free test 234) and the highest being 23 (free test 167) on a scale of 17-56. I’m on self-TRT now and want to make sure I get the most out of it by learning about this issue.
So far what I have learned is that SHBG rises with age, and that low SHBG is somehow related to insulin resistance. I can’t find any answers on how to treat this (some say none are possible). The suggestions have been a low fat, low carb high protein diet (this is no way to live, fat is important and low-carb only works with high-fat diets) and something to do with liver cleanses.
Any thoughts here?