I was aware that ibuprofen for DOMS was bad. But this is news. Ibuprofen can - and I’ll stress CAN lead to infertility… And I wonder if “compensated hypogonadis” - which is a testosterone imbalance has wider effects? However given the wide use of NSAI’s in contact sports like rugby and NFL etc I can’t see it being a game changer.
It looks as is the study took place over 6 weeks with the men taking 600mg a day. At the end of which normal testicular function was impeded. Including testosterone production.
When the testicals stop working it created a condition called compensated hypogonadis.
This is linked to all sorts of issues, impaired fertility, depression, heart failure, and stroke.