I noticed that Bill mentioned that the topicals might have some site specific action. From what I understand, Andro/Nandro topical applications produce a ‘reservoir’ which is slowly absorbed and circulated systemically. Now, I know this is probably the most uninformed question you may have ever been asked, but if I don’t apply the topicals to say, my arms or back does this mean that they might experience less growth compared to sprayed areas?
I also wanted to ask about the opposite; i.e. gels/topicals that contain meds that are supposed to work locally to prevent systemic side effects. I can't see how some meds will work primarily in a site specific manner while others don't since they are both being absorbed through the skin in the same manner.