Selective Hypopituitarism Anecdotes and Sources?

So, my pithuitary hormones are all well, except three of them: LH (low), FSH (low), and TSH (high). To be honest, I don’t know if my oxytocin and ADH are ok, but I am assuming they are; I will test for them when I can. The other hormones are all “normal”–and healthy.

Anyways, how is this possible? How can the pituitary (because of tumor or empty sella turcica) be overproducing some hormones and underproducing others? Or can it be caused solely by the hypothalamus? OR could this be a mix of hypothalamus underproducing GnRH only and my thyroid not responding to TSH (so low T3/T4 not sending feedback and TSH continuing to be secreted)? Any anecdotes, ideas, or sources where to search are welcomed.

You need to post your lab results, all available in list format with ranges.

“normal” is a dirty little secret, often masking problems.

TSH is elevated because your hypothalamus is not seeing enough fT3 and rT3 can be interfering. Oral body temperatures may be low, see later on for that, and outer eyebrows may be sparse.

LH/FSH can be low if E2 and/or prolactin is elevated. There can be pituitary damage from blows to the head or adinoma that does not affect all pituitary hormones.


Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.

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